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Faculty/course name/academic level:

Medical School, Pharmaceutical Sciences, PhD

Course status

Accreditation is in progress

Starting date(s) (following optional prep. course)


Max number of students

2 students/each Program (10 students)

Min number of students


Duration of the course

6 semesters (30 months)

Language requirements

B2 level English language examination (TOEFL/IELTS/Other)

The programme consists of 5 modules as follows:


Isolation and structure of biologically active compounds

Optimalization of drug therapy

Drug metabolism of the intestine



The module “Isolation and structure of biologically active compounds” includes 12 topics, the main topics are:

  • Isolation and investigation of naturally occuring carotinoids.
  • Separeting, determination of biologically active compounds.
  • Examination of structure-activity relationship of chalcones and chalcone analogues.
  • Synthesis and pharmacological investigation of carotinoid dendrimers and water-soluble carotinoids.
  • Investigation of active compounds in herbal products.
  • Investigation of antimicrobal and antioxidant effect of honey.
  • Isolation and investigation of pharmacological activity of herbal compounds with anti-inflammatory effect.
  • The polimorphism of herbal plants: morphophysiological investigations and examination of the active ingredients.
  • Etnopharmacobotany: collection of herbal-knowledge in Transylvania, investigation of taxones of herbal plants used in folk medicine.

The module “Optimalization of drug therapy” includes 6 topics, the main topics are:

  • Bioinformatical matrix of drug interactions
  • Development of a database and software for prevetive screening of drug interactions,

interactions triggered by the simultanous administration of medicines, medical    products and diary supplements

  • Optimalization of drug therapy using pharacogenetic investigations
  • Examination of hazards of drug distribution using the internet.

The module “Drug metabolism of the intestine” includes 3 topics, the main topics are:

  • Investigation of drug-elimination in the liver and small intestine.
  • The effect of pathological conditions on elminination of xenobiotics.
  • Investigation of physico-chemical properties influencing the adsorption from the small intestine of phenolic compounds.

The module “Toxicology” includes 2 topics:

  • The role of phosphate-transporters in the absorption, biotransformation and elimination of arsenate.
  • Investigation of cytotoxic and cytoprotective effect of chalcones and analogues.

The module “Neuropharmacology” includes 8 topics, the main topics are:

  • Anti-inflammatory effect of ligands of the somatostatine receptors.
  • The role of neuropeptides with inflammatory and anti-inflammatory effect on diseases accompanied by inflammatory of the skin, joints and intestine.
  • Investigation of the mechanism and pharmacological modulation of terminal hyperalgesy.
  • In vitro investigation of migration inhibitor factors (MIF) of macrophages.
  • The role of peptide mediators  in the development of fever.
  • The effect of perinatal factors on the regulation of energy balance.

University of Pécs